Galaxy Deployment on Heterogenous Hardware

Thumbnail Image
If you need an accessible version of this item, please email your request to so that they may create one and provide it to you.
Journal Title
Journal ISSN
Volume Title
Indiana University, like many institutions, houses a heterogenous mixture of compute resources. In addition to university resources, the National Center for Genome Analysis Support, the Extreme Science and Engineering Discovery Environment, and the Open Science Grid all provide resources to biologists with NSF affiliations. Such a diverse mixture of compute power and services could be applied to address the equally diverse set of problems and needs in the bioinformatics field. Many software suites are well suited for large numbers of fast CPUS, such as phylogenetic tree building algorithms. De novo assembly problems really crave a machine with lots of RAM to spare. Alignment and mapping problems where each input is a separate invocation lend themselves perfectly to high-throughput, heavily distributed compute systems. Galaxy is a web interface that acts as a mediator between the biologist and the underlying hardware and software - in an ideal setup, Galaxy would be able to delegate work to the best suited underlying infrastructure. We present an instance of Galaxy at Indiana University, installed and maintained by NCGAS, that takes advantage of a variety of compute resources to increase utilization and efficiency. The OSG is a distributed grid through which Blast jobs can be run. IU, NCGAS and XSEDE jointly support Mason, a 512Gb/node system. For IU users, Big Red 2 is the first university-owned petaFLOPS machine. Connecting these resources to Galaxy and using the best tool for the job results in the best performance and utilization - everyone wins.
Talk presented at Galaxy Community Conference 2014, June 30 - July 2, 2014. Video is available at URL:
galaxy, hpc, biology, genomics
Link(s) to data and video for this item
Items indicated with a © are under copyright and used here with permission. Such items may not be reused without permission from the holder of copyright except where license terms noted on a slide permit reuse. Except where otherwise noted, contents of this presentation are copyright 2011 by the Trustees of Indiana University. This document is released under the Creative Commons Attribution 3.0 Unported license ( This license includes the following terms: You are free to share – to copy, distribute and transmit the work and to remix – to adapt the work under the following conditions: attribution – you must attribute the work in the manner specified by the author or licensor (but not in any way that suggests that they endorse you or your use of the work). For any reuse or distribution, you must make clear to others the license terms of this work.