MCB10014, Genome Informatics for animals and plants related NSF Award: 0640462, Shared genome database informatics and cyberinfrastructure
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2013-07
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The primary research focus is developing for and using shared cyberinfrastructure for assembly, annotation and comparative analysis of new organism genomes. This fifth year effort has produced substantial results with EvidentialGene, introduced in prior reports. In conjunction with this software engineering, it has been used to produce well-annotated gene sets for several animal and plant species. An engineering discovery has been made and substantiated: that gene construction from mRNA-seq data is now surpassing genome-based gene predictions in biological accuracy. This has ramifications to many areas of biosciences and related health and agriculture fields that rely on accurate gene information from animals and plants. The software developed in this project is now being used by others to advance their gene discovery for a range of organisms.
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Technical Report