List of base-pair substitutions found in 38 mutation accumulation lines of Wild-type 3K (E. coli PFM2) from Lee et al. PNAS (2012) - doi:10.1073/pnas.1210309109

Simple item page
dc.contributor.authorLee, Heewooken
dc.contributor.authorPopodi, Ellenen
dc.contributor.authorTang, Haixuen
dc.contributor.authorFoster, Patricia Len
dc.date.accessioned2012-12-10T18:46:25Zen
dc.date.available2012-12-10T18:46:25Zen
dc.date.issued2012-09-18en
dc.description.abstractList of base-pair substitutions found in 38 mutation accumulation lines of Wild-type (E. coli PFM2)en
dc.description.fileExcel file format (xlsx). Each row is associated with a recovered base-pair substitution. The first column indicates the name of the MA line. The second column is the position of the base-pair substitution. The third, fourth, and fifth columns are the reference base, consensus base, and observed base, respectively. The reference base is taken from the reference genome (Ecoli K-12 MG1655, NC_000913.2 from NCBI). The consensus base is the base of the starting strain determined by sequencing of all WT MA lines [refer to Lee et al. PNAS (2012) ]. The observed base is the mutated base observed in the MA line designated by column 1.en
dc.description.methodologyPlease refer to Lee et al. PNAS (2012) - doi:10.1073/pnas.1210309109en
dc.description.sponsorshipMultidisciplinary University Research Initiative Award W911NF-09-1-0444 from the US Army Research Officeen
dc.identifier.citationLee, H., Popodi, E., Tang, H., & Foster, P. L. (2012). Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing. Proceedings of the National Academy of Sciences.en
dc.identifier.urihttps://hdl.handle.net/2022/15193en
dc.language.isoen_USen
dc.relation.isversionofThe base-pair substitutions and short indels (up to 4bp) found in the MutL lines are also available in VCF file format(Variant Call Format) from NCBI's Short Read Archive (SRA) under the accession number SRA054030. The raw sequencing data is also available under the same accession number, Currently, the VCF file format is not fully supported by SRA so the data are available from the provisional page of SRA, located at http://trace.ncbi.nlm.nih.gov/Traces/sra/sra.cgi?view=provisionalen
dc.subjectevolutionen
dc.subjectmutation accumulationen
dc.subjectneutral mutationen
dc.subjectmutational hotspotsen
dc.titleList of base-pair substitutions found in 38 mutation accumulation lines of Wild-type 3K (E. coli PFM2) from Lee et al. PNAS (2012) - doi:10.1073/pnas.1210309109en
dc.typeDataseten

Files

Original bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
WT_bps_IUSCHOLAR.xlsx
Size:
45.28 KB
Format:
Unknown data format
Download

Collections

Data
Can’t use the file because of accessibility barriers? Contact us with the title of the item, permanent link, and specifics of your accommodation need.