List of base-pair substitutions found in 34 mutation accumulation lines of MutL deficient (MutL-) strain of E. coli PFM2 from Lee et al. PNAS (2012) - doi:10.1073/pnas.1210309109
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2012-09-18
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Abstract
List of base-pair substitutions found in 34 mutation accumulation lines of MutL deficient (MutL-) strain of E. coli PFM2
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evolution, mutation accumulation, neutral mutation, mutational hotspots
Citation
Lee, H., Popodi, E., Tang, H., & Foster, P. L. (2012). Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing. Proceedings of the National Academy of Sciences.
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The base-pair substitutions and short indels (up to 4bp) found in the MutL lines are also available in VCF file format(Variant Call Format) from NCBI's Short Read Archive (SRA) under the accession number SRA054031. The raw sequencing data is also available under the same accession number, Currently, the VCF file format is not fully supported by SRA so the data are available from the provisional page of SRA, located at http://trace.ncbi.nlm.nih.gov/Traces/sra/sra.cgi?view=provisional
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