List of base-pair substitutions found in 21 mutation accumulation lines of Wild-type 6K (E. coli PFM2)
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The base-pair substitutions along with short indels (upto 4bp) found in Wild-type lines are also available in VCP file format(Variant Call Format) from NCBI's Short Read Archive (SRA) under the accession number of SRA054030. Under the same accession number, raw sequencing data is also available. Currently, VCF file is not fully supported by SRA so it's available through the provisional page of SRA, located at http://trace.ncbi.nlm.nih.gov/Traces/sra/sra.cgi?view=provisional en_US
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Abstract
List of base-pair substitutions found in 21 mutation accumulation lines of Wild-type 6K (E. coli PFM2)
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Keywords
evolution, mutation accumulation, mutational hotspots, neutral mutation
Citation
Lee, H., Popodi, E., Tang, H., & Foster, P. L. (2012). Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing. Proceedings of the National Academy of Sciences.
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