Show simple item record Hardee, Jillian E. Thompson, James C. Puce, Aina 2019-02-25T18:33:21Z 2019-02-25T18:33:21Z 2008-01
dc.identifier.citation Hardee JE, Thompson JC, Puce A. The left amygdala knows fear: Laterality in the amygdala response to fearful eyes. Social Cognitive and Affective Neuroscience 3: 47-54. en
dc.description.abstract The detection of threat is a role that the amygdala plays well, evidenced by its increased response to fearful faces in human neuroimaging studies. A critical element of the fearful face is an increase in eye white area (EWA), hypothesized to be a significant cue in activating the amygdala. However, another important social signal that can increase EWA is a lateral shift in gaze direction, which also serves to orient attention to potential threats. It is unknown how the amygdala differentiates between these increases in EWA and those that are specifically associated with fear. Using functional magnetic resonance imaging, we show that the left amygdala distinguished between fearful eyes and gaze shifts despite similar EWA increases whereas the right amygdala was less discriminatory. Additional analyses also revealed selective hemispheric response patterns in the left fusiform gyrus. Our data show clear hemispheric differences in EWA-based fear activation, suggesting the existence of parallel mechanisms that code for emotional face information. en
dc.language.iso en en
dc.publisher Social Cognitive and Affective Neuroscience en
dc.relation.isversionof en
dc.subject amygdala en
dc.subject fMRI en
dc.subject fusiform gyrus en
dc.subject fear en
dc.subject eye gaze en
dc.title The left amygdala knows fear: laterality in the amygdala response to fearful eyes en
dc.type Article en
dc.identifier.doi 10.1093/scan/nsn001

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