Show simple item record LeClair, Alexander Wells, Jonathan Nair, T. Murlidharan 2013-12-20T19:58:40Z 2013-12-20T19:58:40Z 2013-10
dc.description.abstract The human genome is tightly folded to fit within the restricted space of the nucleus. One of the key goals in understanding the folding principles of DNA is to unravel the mysteries of how functional elements that are separated from each other are brought together. Long-range interactions between folded segments of chromosomes form complex three-dimensional networks and are fundamental in controlling gene expression. These long-range interactions have been observed using chromosome conformation capture (3C). This Hi-C data contains a wealth of information on the nearest-neighbor influence on the deviation of the DNA axis that can be modeled theoretically. We have developed a tool using WebGL to visualize the modeled structures. en_US
dc.language.iso en_US en_US
dc.publisher Indiana University South Bend en_US
dc.subject Human genome en_US
dc.subject WebGL (Computer program language) en_US
dc.title DNAV: A WebGL Based Tool for Visualizing the Twists and Turns in the Human Genome en_US
dc.type Presentation en_US

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