Data

 

Recent Submissions

  • DeHart, Caroline J; Fellers, Ryan T; Fornelli, Luca; Kelleher, Neil L; Thomas, Paul M (Methods in Molecular Biology, Springer, )
    Traditional bottom-up mass spectrometry-based proteomics relies on the use of an enzyme, often trypsin, to generate small peptides (typically < 25 amino acids long). In top-down proteomics, proteins remain intact and are ...
  • De Hart, Caroline J; Fellers, Ryan T; Fornelli, Luca; Kelleher, Neil L; Thomas, Paul M (Methods in Molecular Biology, Springer, 2016)
    Traditional bottom-up mass spectrometry-based proteomics relies on the use of an enzyme, often trypsin, to generate small peptides (typically < 25 amino acids long). In top-down proteomics, proteins remain intact and are ...
  • Savaryn, John P.; Toby, Timothy K.; Catherman, Adam D.; Fellers, Ryan T.; LeDuc, Richard D.; Thomas, Paul M.; Friedewald, John J.; Salomon, Daniel R.; Abecassis, Michael M.; Kelleher, Neil L. (Proteomics, 2016-02-19)
    Recent studies utilizing transcriptomics, metabolomics, and bottom up proteomics have identified molecular signatures of kidney allograft pathology. Although these results make significant progress toward non-invasive ...
  • Skinner, Owen S.; Havugimana, Pierre C.; Haverland, Nicole A.; Fornelli, Luca; Early, Bryan P.; Greer, Joseph B.; Fellers, Ryan T.; Durbin, Kenneth R.; Do Vale, Luis H. F.; Melani, Rafael D.; ... (Nature Publishing Group, )
    Efforts to map the human protein interactome have resulted in information about thousands of multi-protein assemblies housed in public repositories, but the molecular characterization and stoichiometry of their protein ...
  • Savaryn, John Paul; Skinner, Owen S.; Fornelli, Luca; Fellers, Ryan T.; Compton, Philip D.; Terhune, Scott S.; Abecassis, Mike M.; Kelleher, Neil L. (Journal of Proteomics, 2015-05-04)
    Measuring post-translational modifications on transcription factors by targeted mass spectrometry is hampered by low protein abundance and inefficient isolation. Here, we utilized HaloTag technology to overcome these ...

Search IUScholarWorks


Advanced Search

Browse

My Account

Statistics

RSS Feeds