Consortium for Top Down Proteomics (CTDP)

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The Consortium for Top Down Proteomics was established in 2012 with the following mission:

To promote innovative research, collaboration and education accelerating the comprehensive analysis of intact proteins.

The consortium exists to bring together disparate researchers in top down proteomics and to educate the world on the study of proteins in the intact state.

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Data [15]
Peer-reviewed Publications [2]

Recent Submissions

Title: Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients Author: Toby, Timothy K.; Kim, Kyunggon; Thomas, Paul M.; Fellers, Ryan T.; LeDuc, Richard D.; Kelleher, Neil L.; Demetris, Anthony J.; Abecassis, Michael M.; Levitsky, Josh M. Date: 2017
Title: A comprehensive pipeline for translational top-down proteomics from a single blood draw Author: Toby, Timothy K.; Fornelli, Luca; Srzentić, Kristina; DeHart, Caroline J.; Levitsky, Josh; Friedewald, John; Kelleher, Neil L. Date: 2016-11
Title: Identification and characterization of human proteoforms by top-down LC-21 tesla FT-ICR mass spectrometry Author: Anderson, Lissa C; DeHart, Caroline J; Kaiser, Nathan K; Fellers, Ryan T; Smith, Donald F; Greer, Joseph B; LeDuc, Richard D; Blackney, Gregory T; Thomas, Paul M; Kelleher, Neil L; Hendrickson, Christopher L Date: 2016
Title: Advancing top-down analysis of the human proteome using a benchtop quadrupole-Orbitrap mass spectrometer Author: Fornelli, Luca; Durbin, Kenneth R; Fellers, Ryan T; Early, Bryan P; Greer, Joseph B; LeDuc, Richard D; Compton, Phillip D; Kelleher, Neil L Date: 2016-08
Title: Accurate Estimation of False Discovery Rates for Protein and Proteoform Identification in Top Down Proteomics Author: Shams, Daniel P; Early, Bryan P; Fellers, Ryan T; Greer, Joseph B; Thomas, Paul M; Fornelli, Luca; LeDuc, Richard D; Schwab, David J; Kelleher, Neil L Date:
Title: Bioinformatics Analysis of Top-Down Mass Spectrometry Data Author: DeHart, Caroline J; Fellers, Ryan T; Fornelli, Luca; Kelleher, Neil L; Thomas, Paul M Date:
Title: Computing challenges in working with genomics-scale data Author: Wu, Le-Shin; Ganote, Carrie Date: 2014-07-23
Title: Introduction to genomics software use on high performance computing systems Author: Wu, Le-Shin; Ganote, Carrie Date: 2014-07-22
Title: Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite Author: De Hart, Caroline J; Fellers, Ryan T; Fornelli, Luca; Kelleher, Neil L; Thomas, Paul M Date: 2016
Title: Comparative top down proteomics of peripheral blood mononuclear cells from kidney transplant recipients with normal kidney biopsies or acute rejection Author: Savaryn, John P.; Toby, Timothy K.; Catherman, Adam D.; Fellers, Ryan T.; LeDuc, Richard D.; Thomas, Paul M.; Friedewald, John J.; Salomon, Daniel R.; Abecassis, Michael M.; Kelleher, Neil L. Date: 2016-02-19
Title: An informatic framework for decoding protein complexes by top-down mass spectrometry Author: Skinner, Owen S.; Havugimana, Pierre C.; Haverland, Nicole A.; Fornelli, Luca; Early, Bryan P.; Greer, Joseph B.; Fellers, Ryan T.; Durbin, Kenneth R.; Do Vale, Luis H. F.; Melani, Rafael D.; Seckler, Henrique S.; Nelp, Micah T.; Belov, Mikhail E.; Horning, Stevan R.; Makarov, Alexander A.; LeDuc, Richard D.; Bandarian, Vahe; Compton, Philip D.; Kelleher, Neil L. Date:
Title: Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry Author: Savaryn, John Paul; Skinner, Owen S.; Fornelli, Luca; Fellers, Ryan T.; Compton, Philip D.; Terhune, Scott S.; Abecassis, Mike M.; Kelleher, Neil L. Date: 2015-05-04
Title: Characterization of Native Protein Complexes Using Ultraviolet Photodissociation Mass Spectrometry Author: O’Brien, John P.; Li, Wenzong; Zhang, Yan; Brodbelt, Jennifer S.
Title: Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry Author: Kellie, JF; Higgs, RE; Ryder, JW; Major, A; Beach, TG; Adler, CH; Merchant, K; Knierman, MD Date: 2014-07-23
Title: Ultraviolet Photodissociation for Characterization of Whole Proteins on a Chromatographic Time Scale. Author: Cannon, JR; Cammarata, MB; Robotham, SA; Cotham, VC; Shaw, JB; Fellers, RT; Early, BP; Thomas, PM; Kelleher, NL; Brodbelt, JS Date: 2/21/2014
Title: Optimizing capillary electrophoresis for top-down proteomics of 30-80 kDa proteins. Author: Li, Yihan; Compton, Philip D.; Tran, John C.; Ntai, Ioanna; Kelleher, Neil L. Date: 1/14/2014
Title: Autopilot: An Online Data Acquisition Control System for the Enhanced High-throughput Characterization of Intact Proteins Author: Durbin, Kenneth; Fellers, Ryan; Ioanna, Ntai; Kelleher, Neil; Compton, Philip Date: 2014

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