Browsing by Author "Mukhopadhyay, Suchetana"

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  • Mukhopadhyay, Suchetana; Cheng, Fan (Elsevier, 2011-02-19)
    Alphaviruses are comprised of a nucleocapsid core surrounded by a lipid membrane containing glycoprotein spikes. Previous work demonstrated that in vitro assembled core-like particles are similar in structure to the ...
  • Parrott, Megan M.; Sitarski, Sarah A.; Arnold, Randy J.; Picton, Lora K.; Hill, R. Blake; Mukhopadhyay, Suchetana (American Society for Microbiology, 2009)
    Alphavirus particles are covered by 80 glycoprotein spikes that are essential for viral entry. Spikes consist of the E2 receptor binding protein and the E1 fusion protein. Spike assembly occurs in the endoplasmic reticulum, ...
  • Kao, C. Cheng; Ranjith-Kumar, C. T.; Mukhopadhyay, Suchetana; Zlotnick, Adam; Valverde, Rodrigo A.; Tragesser, Brady J.; Bhardwaj, Kanchan; Chen, Alice; Yi, Guanghui; Lai, Yvonne (PLoS, 2011-10)
    Toll-like Receptor 3 (TLR3) detects double-stranded (ds) RNAs to activate innate immune responses. While poly(I:C) is an excellent agonist for TLR3 in several cell lines and in human peripheral blood mononuclear cells, ...
  • Mukhopadhyay, Suchetana; Zlotnick, Adam (Elsevier, 2010-12-28)
    Assembly of virus capsids and surface proteins must be regulated to ensure that the resulting complex is an infectious virion. In this review, we examine assembly of virus capsids, focusing on hepatitis B virus and ...

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