Browsing by Author "Lai, Yvonne"

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  • Kao, C. Cheng; San Mateo, Lani; Dragnea, Bogdan; Wu, Linda H.; Jordan, Jarrett L.; Wen, Yahong; Ranjith-Kumar, C. T.; Bhardwaj, Kanchan; Adhikarakunnathu, Sreedevi; Lai, Yvonne (PLoS, 2011-10)
    Background: Toll-like Receptor 3 (TLR3) detects viral dsRNA during viral infection. However, most natural viral dsRNAs are poor activators of TLR3 in cell-based systems, leading us to hypothesize that TLR3 needs additional ...
  • Kao, C. Cheng; Ranjith-Kumar, C. T.; Mukhopadhyay, Suchetana; Zlotnick, Adam; Valverde, Rodrigo A.; Tragesser, Brady J.; Bhardwaj, Kanchan; Chen, Alice; Yi, Guanghui; Lai, Yvonne (PLoS, 2011-10)
    Toll-like Receptor 3 (TLR3) detects double-stranded (ds) RNAs to activate innate immune responses. While poly(I:C) is an excellent agonist for TLR3 in several cell lines and in human peripheral blood mononuclear cells, ...

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